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You must code: Whether the patient has a crisis The exact type of Crisis Any associated conditions For example: D57.01 Sickle-cell disease with acute chest syndrome D57.03 With splenic sequestration D57.00 Without Crisis If the patient is NOT in Crisis, say it clearly in the note

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Bruceine A inhibits TGF-1/Smad pathway in pulmonary fibrosis by blocking gal3/TGF-1 interaction

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